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Research for Over 100 Years

Developed and manufactured in Germany 

Innovative Key Ingredient

Research for Over 100 Years

Developed and manufactured in Germany 

Innovative Key Ingredient

Bioniq® Dental Science: Made in Germany

 Close-up of a tooth surface under an electron microscope in shades of blue; at the top, a seal featuring a microscope symbol and the text “Scientifically developed & tested”

Dr. Wolff's Research

Our hydroxyapatite formulations are developed in-house in Bielefeld and they have been tested in international studies.

Schematic representation of the hydroxyapatite crystal structure with the chemical formula Ca₅(PO₄)₃(OH) on a blue background.

Hydroxyapatite

So-called "artificial tooth enamel" is based on the principle of bionics. Through the production of biomimetic hydroxyapatite, researchers have succeeded in replicating a mineral substance and combining it with toothpaste. 

Close-up of a human eye in shades of blue with graphic, technical markings symbolizing the principle of bionics.

The Principle of Bionics

The term "bionics" describes the combination of biology and technology. It involves applying a natural phenomenon to a technical system; for example, the camera lens was modeled after the human eye.  

Our Products

 Various dental care products from Dr. Wolff’s Bioniq, including toothpaste, and special formulas for gum care, arranged against a light-colored background.

Our hydroxyapatite formula is based on the principle of bionics. Through biomimetic hydroxyapatite, researchers have succeeded in replicating a natural mineral with and combining it with toothpaste.

Studies : Proven Effectiveness

  • Clinical Trial : 17 

    A meta-analysis of 17 scientific studies shows that hydroxyapatite significantly whitens tooth enamel.1

  • Clinical Trial : 90%

    In a clinical double‑blind study with 140 participants, an improvement in pain sensitivity was observed in 90% of those who used a toothpaste containing hydroxyapatite.2

     

  • Clinical Trial : 92.6%

    In an in vitro study, 92.6% of stains were removed by brushing with Bioniq® White Filler Hydroxyapatite Toothpaste.3

  • Clinical Trial : 99.3%

    An in‑vitro study confirmed that hydroxyapatite can neutralize up to 99.3% of the acid contained in cola and serves as both erosion protection and a source of calcium.4

Dental Care by Dr. Wolff: Bioniq® Research: Standing the Test of Time

Our Commitment to Research and Innovation in Dental Care

Dr. Wolff Dental Care: A scientist in a white lab coat and safety goggles holds a small tube of white powder, symbolizing Bioniq’s research into fluoride-free dental care with hydroxyapatite

Bioniq® is different because Dr. Wolff is different. And so is our research. We don’t just sell dental care products with clinically tested ingredients—we also actively work to advance research in dental health.

What makes Bioniq® special is the combination of our own research and international evidence of efficacy. Our formulations are developed here in Bielefeld—and their effectiveness has been confirmed in clinical studies worldwide.
JE

Dr. Joachim Enax

Senior Scientist, Oral Care

Dental Care Products Containing Hydroxyapatite

FAQ : Frequently Asked Questions

Apatites, such as hydroxyapatite, are minerals and belong to the class of calcium phosphates. There are a number of different calcium phosphates. Hydroxyapatite is the most stable and, for humans, the most important calcium phosphate, as it forms the mineral phase of teeth and bones. The chemical formula for hydroxyapatite is Ca5(PO4)3(OH). 

Hydroxyapatite plays an essential role in the human body. It forms the basis of teeth and bones. In both cases, hydroxyapatite is responsible for their hardness. Compared to many other key ingredients in dental care, hydroxyapatite is a substance produced naturally by the body. 

Many whitening toothpastes typically contain highly abrasive particles and/or peroxides, which aggressively remove stains but can damage teeth and enamel and often cause tooth sensitivity. The resulting roughened tooth surface can actually cause new stains to adhere even more strongly.

The whitening technology in Bioniq® White Filler Hydroxyapatite Toothpaste has the opposite effect: whitening ingredients help gently and effectively remove discoloration. White hydroxyapatite creates a microfine white layer forms on the tooth surface. The teeth also feel smoother right away.

Bioniq® uses the innovative ingredient hydroxyapatite as its main ingredient. Hydroxyapatite plays an essential role in the human body. It forms the basis of teeth and bones. In both cases, hydroxyapatite is responsible for their hardness. Compared to many other ingredients in dental care, hydroxyapatite is a substance produced naturally by the body.

Sources

  1. Limeback, H., Meyer, F., Enax, J. (2023): Tooth Whitening with Hydroxyapatite: A Systematic Review, Dent J, 12; 11(2):50.
  2. Hüttemann, R. W., Dönges, H. (1987): Treatment of dentin hypersensitivity with hydroxyapatite, Dtsch Zahnarztl Z, 42(5):86-8.
  3. Limeback, H., Meyer, F., Enax, J. (2023): Tooth Whitening with Hydroxyapatite: A Systematic Review, Dent J, 12; 11(2):50.
  4. Fandrich, P., Stammler, F. J., Enax, J., et al. (2026): In vitro study on the neutralization potential of particulate hydroxyapatite in erosive acids. BDJ Open 12:25.